Originally, Penzance was the chief town in Madron parish, but as it grew that church was not able to support the growing population of the borough. Details of Churches in Penzance and the local district are available on-line.
- Anglican. "The parish church of Penzance is at Madron about a mile and a half from the town: the living is a perpetual curacy, in the gift of the corporation; the Rev. C. N. Le Grice is the present curate. In the town are, a chapel of ease under Madron parish, with several meeting houses for dissenters and a jewish synagogue."(Pigot & Co 1830 Directory).
Penzance was, therefore, originally a Chapelry of Madron. However, the growth of the Town of Penzance required a church in the town, and the building of a new church, dedicated to St Mary, was commenced on 17th August 1832, and the structure was opened for divine service on 15th November 1835.
At the end of the 20th century, the Town of Penzance consisted of three ecclesiastical Anglican parishes:- St Mary the Virgin. This is the oldest parish covering Penzance. The parish was separated from Madron parish in 1835, and formally became a parish in its own right in 1871.
- St John the Baptist. This is a modern parish in Penzance, created 1847, and is situated in the north-west part of the town.
- St Paul's. St Paul's parish is also a relatively modern parish of Penzance, situated in the southern part of the town. It was created from part of Penzance in 1852, but it merged with St Mary's parish in 2000.
- Roman Catholics. The Church of Our Lady was officially opened on 26th October 1843. At that time there were very few Catholics in the area. The dedication was probably influenced by the fact that the Immaculate Conception of Our Lady was to be defined and promulgated in 1854, by Pope Pius IX (1846-1878). It may be of some interest to know that in 1497 the University of Paris and, apparently, subsequently many other seats of learning demanded of their students an oath to defend and uphold the Immaculate Conception of Mary.
The dignified, grandiose, lofty interior of this Cornish church is worth a visit. A new east window was fitted over the High Altar in 1991, constructed in the workshops of Mr Roy Mead of Falmouth. The new window, providing double glazing against the existing, is built up from a composite of textured water glasses from America and from various Cathedral glasses.
The RC Parish Priest of Penzance is also responsible for the Mission on the Isles of Scilly and the small church of Our Lady Star of the Sea on St Mary's. - Non-Conformist.
- The Society of Friends (Quakers) had a Meeting House in Causewayhead Street.
- A Baptist Chapel in Clarence Street was built in 1836.
- The Congregationalist Chapel in Market Jew Street was built in 1662.
- The Bible Christian chapel in High Street was opened in May 1879, and enlarged 1893.
- The Primitive Methodists had a chapel in Mount Street.
- There is a Wesleyan Chapel in Heamoor, which is known as the Wesleyan Rock Chapel.
- The Wesleyan Methodist Chapel in Chapel Street was erected in 1814 and enlarged in 1864. It is a building of granite with a portico of the Doric Order, and has seating for 1800 persons; it is still open at the beginning of the 21st century.
- The Free Methodists had a chapel in Parade Street.
- Jews. There was a Jewish Synagogue in New Street; it was first used in 1768 and rebuilt in 1806. The Synagogue continued in use until 1913, when it was sold to the Plymouth Brethren; it is now the Gospel Hall.